Endocrine Abstracts

Dehydroepiandrosterone (DHEA) and its sulphate (DHEAS) are weak adrenal androgens, which may exert anabolic effect on bone tissue.We have measured serum DHEAS levels and bone mineral density in lumbar spine and femoral neck in 131 healthy, agile, postmenopausal women aged 59–89. There were no diseases which aggravate bone loss and no hormonal replacement therapy in medical history of participants.Women were divided into groups...

54-year old woman with Graves’ disease was admitted to Endocrinology Department because of severe thyrotoxicosis and antithyroid drugs inolerance. The apathetic form of thyrotoxicosis was diagnosed; she lost 12 kg during 3 months and she had heavy muscle weakness. Previously she demonstrated allergic skin reactions (macular rushes) after both: Methimazole and Propylthiouracil. At admission her TSH was 0.001 mU/l, fT3 24 pg/ml, fT4 37 pmol/l. Lithium, propranolol and gluco...